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Automation, Standardization & Migration to Open Source
Trusted by:
We optimize analytics data workflows, help adopt data standards, automate regulatory deliverables, and migrate you to validated open-source solutions or help you adopt a multilanguage setup while automating the most time-intensive parts of your process.
Results That Compound Across Your Organization
From operational speed to strategic positioning, our automation and migration work delivers impact at every level of your organization.
Operational Acceleration
We eliminate repetitive manual work. Submission dossier creation for ICH eCTD modules, including Clinical Summary and Study Reports built on SDTM/ADaM datasets, becomes streamlined.
Strategic Advantages
Open-source solutions deliver significant cost reduction while eliminating vendor lock-in. Standardizing now lays the foundation for AI-driven analytics tomorrow.
Talent Advantage
Modern open-source tooling attracts the next generation of data scientists. Your existing team stays engaged because the expertise is transferable and career-building.
How We Helped Our Partners
Cut Submission Dataset Exports from 12 Hours to 20 Minutes
A global pharmaceutical company reduced a 40GB submission dataset export from an overnight run to about 20 minutes, making delivery timelines more predictable for submission teams.
Full-Spectrum Capabilities
From R/Python ecosystem work to AI-driven TLF generation, we cover the entire analytics modernization lifecycle.
Timeline
R & Python Workflows
Package development, testing, documentation, open-releasing and validation across your analytics ecosystem.
Engineering
Productionizing & Scaling
Best engineering practices applied to existing fragmented workflows and analytics infrastructure.
Standards
ARD/ARS Implementation
Working with CDISC datasets, generating metadata, and implementing analysis results standards.
AI
Automated TLF Generation
Leverage AI for automated Tables, Listings, and Figures generation from standardized data.
Delivery
Regulatory Submissions
End-to-end support for submission dossier creation aligned with ICH eCTD requirements.
#Why Appsilon
Not just a vendor.
A force multiplier.
We bring ecosystem access, regulatory experience, and elite talent that compounds your capabilities.
Pharmaverse Council Members
We sit on the pharmaverse council, develop core packages, and contribute to the ecosystem. You gain access to our deep connections and collaborative innovation.
Proven with Regulators
Partnered with Eli Lilly and R Consortium on pilot FDA submissions. We know what regulators expect and how to deliver it with open-source tooling.
Real Pharma Experience
We've helped 8 of the top 10 pharma companies modernize their analytics workflows. We understand the regulatory constraints, organizational dynamics, and technical debt you're working with.
Core Open Source Contributors
Appsilon engineers serve as core contributors to the {teal} framework, sponsored by Roche. Our team shapes the tools your teams rely on.
How We Work With You
From operational speed to strategic positioning, our automation and migration work delivers impact at every level of your organization.
Weeks 1–3
Discovery & Audit
Audit your SAS codebase, map regulatory workflows, identify automation opportunities, and define the pilot scope — typically one study's TLF pipeline.
Weeks 3–8
Standards & Foundation
Set up validated R/Python environment, implement CDISC data standards, establish Git workflows, and validate priority packages with Axon.R.
Weeks 8–16
Automate & Migrate
Automate TLF generation, migrate the pilot workflows to open source, run QC in parallel with SAS, and deliver the first R-based outputs.
Month 4+
Scale Across the Organization
Expand to additional studies and teams. New studies launch on R/Python, SAS licenses phase out naturally. AI-driven analytics become possible.
#Valued by clients worldwide
#Contact Form
Consult with Our Experts for Custom Solutions
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with Appsilon Experts
with Appsilon Experts
We will contact you within 24 hours!
#Our Clients About Appsilon
How It Feels to Work with Us
We rely on Appsilon's expertise to support the build and maintenance of critical clinical reporting software based in R and Shiny.
Data Engineering Lead
Top 10 Pharma Company
Appsilon team is exceptional. The engineers challenge and speak their minds, which helps do justice to the product.
Associate Director
Top 50 Pharma Company
We wouldn't be here where we are now without Appsilon. I want this partnership to keep going and growing.
Human Resources People Partner
Top 10 Pharma Company
Expert Insights
Insights, Inspiration & Distilled Knowledge
SAS to R Migration: How to Import, Process, and Export SAS Files in R
A comprehensive guide on how to seamlessly transition from SAS to R (and integrate SAS data into R) for efficient data analysis.
Eduardo Almeida
Read more
Ebook for Clinical Data & Platform Leaders
Your Guide to Building a Better SCE
Learn how pharma companies are building validated, flexible platforms to support both regulatory submissions and modern analytics.
FAQs
Find clear answers to common questions about GxP compliance, helping you navigate regulations with confidence.
01.
How long does a typical SAS-to-R migration take?
A focused pilot — migrating a single study's TLF pipeline — typically takes 8-12 weeks. Full-scale enterprise migrations are phased over 6-18 months, running parallel to existing SAS workflows to ensure zero disruption.
02.
Will open-source R packages be accepted by regulators like the FDA?
Yes. The FDA accepts submissions using R. Major pharma companies have completed real-world R-based NDAs to the FDA, EMA, and NMPA using Pharmaverse packages. Proper validation is key — which is what Axon.R provides.
03.
What happens to our existing SAS licenses during migration?
We never recommend a hard cutover. Migrations run in parallel — SAS stays fully operational while we build and validate the open-source equivalent. Teams transition gradually, often starting new studies on R/Python.
04.
What makes Appsilon different from other R/Python consulting firms?
We're core contributors to the tools the industry uses. Our engineers build key pharmaverse packages, contribute to {teal}, and sit on the pharmaverse council. You work with the people who shape the ecosystem.
Contact Us
Drive Impact with Appsilon
From custom dashboards and applications to AI-powered solutions and compliant computing environments, our engineers and infrastructure architects accelerate clinical development within fully validated, regulatory-compliant frameworks.